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SepaFlash™ Standard Series

SepaFlash™ Standard Series

Short Description:

Standard Series flash columns are machine packed with UltraPure silica gel using proprietary dry packing technique.

※ UltraPure silica features tight particle size distribution, low level of fines and low trace metal content, neutral pH, controlled water content and high surface area, providing scientists the desired reproducible experimental results.

※ Unique, proprietary dry packing technique guarantees high resolution and reproducibility for everyday purification.

※ Improved pressure rated up to 300 psi.


Product Detail

Application

Video

catalogue

Product Introduction

Standard Series flash columns are machine packed with UltraPure silica gel using proprietary dry packing technique.

※ UltraPure silica features tight particle size distribution, low level of fines and low trace metal content, neutral pH, controlled water content and high surface area, providing scientists the desired reproducible experimental results
※ Unique, proprietary dry packing technique guarantees high resolution and reproducibility for everyday purifications.
※ Improved pressure rated up to 300 psi

Product Parameters

UltraPure irregular silica, 40–63 µm, 60 Å (surface area 500 m2/g, pH 6.5–7.5, loading capacity 0.1–10%)
Item Number Column Size Sample Size(g) Flow Rate(mL/min) Cartridge Length (cm) Cartridge ID (mm) Max. Pressure(psi/bar) Quantity/Box
Small Large
S-5101-0004 4 g 4 mg–0.4 g 15–40 105.8 12.4 300/20.7 36 120
S-5101-0012 12 g 12 mg–1.2 g 30–60 124.5 21.2 300/20.7 24 108
S-5101-0025 25 g 25 mg–2.5 g 30–60 172.7 21.3 300/20.7 20 80
S-5101-0040 40 g 40 mg–4.0 g 40–70 176 26.7 300/20.7 15 60
S-5101-0080 80 g 80 mg–8.0 g 50–100 248.5 30.9 200/13.8 10 20
S-5101-0120 120 g 120 mg–12 g 60–150 261.5 37.2 200/13.8 8 16
S-5101-0220 220 g 220 mg–22 g 80–220 215.9 59.4 150/10.3 4 8
S-5101-0330 330 g 330 mg–33 g 80–220 280.3 59.8 150/10.3 3 6
S-5101-0800 800 g 800 mg–80 g 100–300 382.9 78.2 100/6.9 3 /
S-5101-1600 1600 g 1.6 g–160 g 200–500 432.4 103.8 100/6.9 2 /
S-5101-3000 3000 g 3.0 g–300 g 200–500 509.5 127.5 100/6.9 1 /

※ Compatible with all flash chromatography systems on the market.

High-quality irregular alumina, 50–75 µm, 55 Å (pH: acidic 3.8–4.8, neutral 6.5–7.5, basic 9.0–10.0; surface area 155 m2/g, loading capacity 0.1–4%)
For acidic alumina, replace “N” with “A” in item number, and for basic alumina with “B”.
Item Number Column Size Sample Size(g) Flow Rate(mL/min) Cartridge Length (cm) Cartridge ID(mm) Max. Pressure(psi/bar) Quantity/Box
Small Large
S-8601-0004-N 8 g 8 mg–0.32 g 10–30 105.8 12.4 300/20.7 36 120
S-8601-0012-N 24 g 24 mg–1.0 g 15–45 124.5 21.2 300/20.7 24 108
S-8601-0025-N 50 g 50 mg–2.0 g 15–45 172.7 21.3 300/20.7 20 80
S-8601-0040-N 80 g 80 mg–3.2 g 20–50 176 26.7 300/20.7 15 60
S-8601-0080-N 160 g 160 mg–6.4 g 30–70 248.5 30.9 200/13.8 10 20
S-8601-0120-N 240 g 240 mg–9.6 g 40–80 261.5 37.2 200/13.8 8 16
S-8601-0220-N 440 g 440 mg–17.6 g 50–120 215.9 59.4 150/10.3 4 8
S-8601-0330-N 660 g 660 mg–26.4 g 50–120 280.3 59.8 150/10.3 3 6
S-8601-0800-N 1600 g 1.6 g–64 g 100–200 382.9 78.2 100/6.9 3 /
S-8601-1600-N 3200 g 3.2 g–128 g 150–300 432.4 103.8 100/6.9 2 /
S-8601-3000-N 6000 g 6.0 g–240 g 150–300 509.5 127.5 100/6.9 1 /

※ Compatible with all flash chromatography systems on the market.

Applications and results with SepaFlash flash columns

SepaFlash™ flash columns offer incredible performance over competitive products due to the higher silica gel quality and innovative packing technique.

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The characteristics for UltraPure irregular silica gel

This high efficient material has an irregular particle shape with smooth edges, a very narrow particle size distribution and the low level of fines offered by Santai, which will optimize your separating power and save your time and money. The irregular silica gel has two kinds of specifications, 40-63 µm and 25-40 µm. Especially, Santai further develops the stable dry packing technique for irregular 25-40 µm silica, and the pre-packed 25-40 µm silica cartridges will show an extraordinary ability in dealing with seperation.

SEM picture of 40-63 μm silica gel

SEM picture of 40-63 μm silica gel             

Product Advantages

Santai’ silica gel also offers these advantages over competitor’s products:

Neutral pH: The pH of Santai’s irregular silica gel is kept between 6.5−7.5. A neutral pH is needed to separate pH sensitive compounds.

Stable water content: Water content of silica gel can affect the selectivity of the silica. Santai’s irregular silica gel has a controlled water content of 4% to 6%.

High surface area: Higher surface area (500 m2/g for 60 Å pore size) provides greater separation power.

Tight particle size distribution and high batch-to-batch reproducibility: A narrower particle size distribution will give a more homogenous packing to collect more concentrated fractions and reduce solvent consumption, which will reduce cost overall. The high batch-to-batch reproducibility of particle size distribution fundamentally guarantees the excellent separation performance. More details please see the SEM picture and particle size distribution of two batches.

Particle size distribution of two batches for 40-63 μm and 25-40 μm silica gel

Particle size distribution

NEW COLUMN SIZE – 5 kg

SepaFlash™ columns are now available in 5 kg size.
which could purify up to 500 grams of the sample in a single run.
It is spin-welded and can stand pressure up to 100 psi (6.9 bar).

※ Reliable, consistent performance from proprietary packing technique.
※ Reinforced cartridge body with maximum operating pressure up to 100 psi.
※ Luer-Lok end fittings compatible with any major flash systems in the market.
※ Able to meet the process scale-up requirements from small-scale to pilot-scale.
※ Pre-packed flash columns enable faster purification runs to save time and solvents.
※ Disposable plastic column body enable easy and safe waste handling.

5 kg

Ultra-pure irregular silica, 40–63 µm, 60 Å (NEW Product) (surface area 500 m2/g, pH 6.5–7.5, loading capacity 0.1–10%)

Item Number Column Size Sample Size Units/Box Flow Rate (mL/min) Cartridge Length (mm) Cartridge ID (mm) Max. Pressure (psi/bar)
S-5101-5000 5 kg 5 g–500 g 1 200–500 770 127.5 100/6.9

※ Compatible with all flash chromatography systems on the market.

Good Separations with SepaFlash™ 5 kg

Sample: Acetophenone and P-Methoxyacetophenone
Mobile Phase: 80% hexane and 20% ethyl acetate
Flow Rate: 250 mL/min
Sample Size: 60 mL
Wave Length: 254 nm

Separations

Chromatographic Parameters:

Column Size tR N Rs T
SepaFlash™ 5kg 50min 617 6.91 1.00

NEW COLUMN SIZE – 10 kg

※ Purify up to 1 kg of the sample in a single run.
※ Specifically sealed with proprietary technique.
※ Reliable, consistent performance from proprietary packing technique
※ Reinforced cartridge body with maximum operating pressure up to 100 psi (6.9bar)
※ Various adaptors for different OD tubings make it compatible any major flash systems in the market
※ Able to meet the process scale-up requirements from small-scale to pilot-scale
※ Pre-packed flash columns enable faster purification runs to save time and solvents
※ Disposable plastic column body enable easy and safe waste handling

5 kg

Ultra-pure irregular silica, 40–63 µm, 60 Å (NEW Product) (surface area 500 m2/g, pH 6.5–7.5, loading capacity 0.1–10%)

Item Number Column Size Sample Size Units/Box Flow Rate (mL/min) Cartridge Length (mm) Cartridge ID (mm) Max. Pressure (psi/bar)
S-5101-010K 10 kg 10 g–1 kg 1 300-1000 850 172.5 100/6.9

※ Compatible with all flash chromatography systems on the market.

Good Separations with SepaFlash™ 10 kg

Sample: Acetophenone and P-Methoxyacetophenone
Mobile Phase: 80% hexane and 20% ethyl acetate
Flow Rate: 400 mL/min
Sample Size: 100 mL
Wave Length: 254 nm

SepaFlash

Chromatographic Parameters:

Column Size tR N Rs T
SepaFlash™ 10kg 65min 446 5.97 1.22

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