FAQs

Clean the solvent filter head completely to remove any impurities. Use ethanol or isopropanol to flush the system completely to avoid immiscible solvent problems.

To clean the solvent filter head, disassemble the filter from the filter head and clean it with a small brush. Then wash the filter with ethanol and blow-dry it. Re-assemble the filter head for future use.

Either switch from normal phase separation to reversed phase separation or vice versa, ethanol or isopropanol should be used as the transition solvent to completely flush out any immiscible solvents in the tubing.

It is suggested to set the flow rate at 40 mL/min to flush the solvent lines and all the internal tubings.

Please reposition the bottom of the column holder after Loosen the screw.

1. The system flow rate is too high for the current flash column.

2. Sample has poor solubility and precipitates from the mobile phase, thus resulting tubing blockage.

3. Other reason causes tubing blockage.

The environment is too wet, or the solvent leakage to the inside of the column holder causes short circuit. Please heat the column holder properly by a hair dryer or a hot air gun after power off.

Solvent leakage might be due to the solvent level in the waste bottle is higher than the height of the connector at the base of the column holder.

Place the waste bottle below the operation platform of the instrument, or quickly move down the column holder after removing the column.

This cleaning function is designed to clean the system pipeline before separation run. If “post-cleaning” has been performed after the last separation run, this step could be skipped. If it is not performed, it is recommended to do this cleaning step as instructed by the system prompt.